• Conferencia en el Edificio QUIFIMA del profesor Nilay Hazari, de la Universidad de Yale, bajo el título: “The Rational Development of Precatalysts for Cross-Coupling and Cross- Electrophile Coupling Reactions”

  • Tuesday, 05 February
  • Edificio QUIFIMA. Campus Miguel Delibes de la Universidad de Valladolid
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    El Instituto CINQUIMA de la Universidad de Valladolid recibe este martes, 5 de febrero, al profesor Nilay Hazari, de la Universidad de Yale, que impartirá la conferencia “The Rational Development of Precatalysts for Cross-Coupling and Cross- Electrophile Coupling Reactions”.

    El Grupo Especializado de Química Organometálica de la RSEQ ha organizado la estancia de Hazari como  Conferenciante Itinerante durante el mes de febrero en España, y, desde el CINQUIMA, nos ha parecido interesante invitarle a impartir una conferencia en Valladolid.

    La conferencia tendrá lugar a las 12:00 h en la sala de conferencias del Edificio QUIFIMA.

    La entrada es libre hasta completar el aforo.

    Abstract:

    Transition metal catalyzed cross-coupling has found applications in diverse areas of chemistry and is
    widely considered to be one of the most powerful and general synthetic methods. Both Ni and Pd
    complexes are now commonly used to facilitate cross-coupling reactions. The mechanism for both Ni and
    Pd catalysts is typically proposed to involve a series of complexes in the M(0) and M(II) oxidation states.
    In this presentation we will describe results that indicate that state-of-the-art Ni and Pd precatalysts form a
    significant quantity of species in the M(I) oxidation state during catalytic reactions. We will describe the
    mechanistic pathways through which these M(I) complexes are formed. The M(I) complexes are
    catalytically inactive and by understanding how they are formed it is possible to stop their generation
    during catalysis. We have used this information to design improved catalytic systems, which are now
    commercially available. The implications of our results to crosselectrophile coupling will also be explored.
     
    Short CV:
    Nilay Hazari was born in Suva, Fiji and spent the first 17 years of his life in Melbourne, Australia. After
    that he moved to Sydney where he received a B.Sc (2002) and an M.Sc (2003) from the University of
    Sydney working with Professor Leslie D Field. He completed a D.Phil (2006) as a Rhodes Scholar at the
    University of Oxford under the supervision of Professor Jennifer C Green and then worked for three years
    as a postdoctoral scholar with Professors John E Bercaw and Jay A Labinger at the California Institute of
    Technology. Nilay began as an Assistant Professor of Chemistry at Yale University in July 2009 and is
    currently a Professor of Chemistry.